Around the world, it is considered that 2.5 billion people are infected or have been infected by hepatitis B virus (HBV), that is to say 1/3 of the world's population.
Natural History of HBV infection is variable, from an asymptomatic carrier status developing spontaneously to recovery, to a chronical hepatitis B, which can progress into cirrhosis and hepatocellular carcinoma.
About 240 million people are suffering from chronic hepatitis and from 0.5 to 1 million people are dying each year because of the infection.
GENERIC HBV Charge Virale
GENERIC HBV Charge Virale test is a quantification tool for HBV viral load for research use only.
The test relies on two main technical stages:
1. Viral DNA extraction by automatic
2. Amplification of the DNA extract by real-time PCR
Target region: S gene
Detection limit: 95 IU/mL for a 250 µL sample
Linearity: 125 to 1.10 IU/mL
Duration: 3 hours (extraction + amplification)
Type of sample: human plasma removed from EDTA