GENERIC HIV DNA Cell [RUO]
While viral load of plasma HIV-1 is a biological marker that quantifies the number of viruses that are circulating, HIV-1 cellular DNA quantifies the number of infected cells in a latent or productive way.
Generic HIV DNA Cell is a research test as part of the evaluation of the HIV-1 reservoir.
This test relies on two main technical stages:
1. DNA extraction by manual method (e.g. silica-based membrane technology)
2. DNA extract real-time amplification
Targeted region: LTR
Detection limit: 40 HIV-1/10 leucocytes DNA copies
Special features: M group, subtypes A to H
Duration: 2 hours 30 minutes (extraction + amplification)
Type of sample: Human whole-blood obtained from an ETDA dry pellet or lymphocytes